Hello guest
Your basket is empty
We provide two pathways to the content. Thematic (chapters that address certain themes, e.g. cultivation, regardless of crop or animal type) and Product (chapters that relate to a specific type of crop or animal). Choose the most applicable route to find the right collection for you. 
Can’t find what you are looking for? Contact us and let us help you build a custom-made collection. 
You are in: All categories > A-Z Chapters > F
Use the Contact form to discuss the best purchasing method for you... Start building your collection today!

Finding causal variants for monogenic traits in dairy cattle breeding

Code: 9781786765666
Matt Littlejohn, Livestock Improvement Corporation (LIC) and Massey University, New Zealand; and Chad Harland, Livestock Improvement Corporation (LIC), New Zealand

Chapter synopsis: Many of the most striking traits we recognise in cattle are caused by one or a small number of large effect mutations. These include breed-defining characteristics such as coat colours and patterns, hair length, and horn status. Many deleterious effects in cattle can also be attributed to single genes, with phenotypic impacts ranging from mild (e.g. crop ears), to severe (embryonic lethality). This chapter will summarise a range of traits impacted by major effect genes in cattle, discussing examples of mutation discoveries with a focus on the methods used to identify these effects. The review includes analysis of emerging technologies and methods being applied to mutation discovery in cattle, examining how new molecular innovations and large-scale genomic data are playing increasingly important roles in causal gene and mutation identification.

DOI: 10.19103/AS.2019.0058.20
Table of contents 1 Introduction 2 Mapping approaches 3 Methods for identifying de novo and multi-allelic mutations 4 Annotation and functional prediction of candidate mutations 5 Implementation in breeding schemes 6 Conclusion and future trends 7 Acknowledgements 8 Where to look for further information 9 References

Also in F

Our site uses cookies. For more information, see our cookie policy. Accept cookies and close
Reject cookies Manage settings