Hello guest
Your basket is empty
We provide two pathways to the content. Thematic (chapters that address certain themes, e.g. cultivation, regardless of crop or animal type) and Product (chapters that relate to a specific type of crop or animal). Choose the most applicable route to find the right collection for you. 
Can’t find what you are looking for? Contact us and let us help you build a custom-made collection. 
You are in: All categories > Open Access
Use the Contact form to discuss the best purchasing method for you... Start building your collection today!

Progress in precise and predictable genome editing in plants with base editing

Code: 9781801460972
Sabine Fräbel, Shai J. Lawit, Jingyi Nie, David G. Schwark, Thomas J. Poorten and Nathaniel D. Graham, Pairwise Plants, USA

Chapter synopsis: Base editors are gene editing tools that allow targeted nucleic acid conversions, most commonly C>T and A>G, through pairing of deamination domains with impaired nucleases. Multiple deaminase domains and architectures have been demonstrated in planta across a wide array of species, with both cytosine and adenine base editing frequencies being observed at over 80%. The ability of base editors to introduce nucleic acid diversity while maintaining the same reading frame should make them powerful tools for plant genetic editing moving forward.

DOI: 10.19103/AS.2020.0082.06

Click here to download
Table of contents 1 Introduction 2 Progress in mammalian systems 3 Cytosine base editing in plants 4 Adenine base editing in plants 5 Broadening protospacer adjacent motif (PAM) accessibility 6 Sequence diversification in crops 7 Off-target base editing 8 Current applications of base editors in crops 9 Conclusion 10 Where to look for further information 11 References

Also in Open Access

Our site uses cookies. For more information, see our cookie policy. Accept cookies and close
Reject cookies Manage settings